We all fall down

CWA # 273
We all fall down
Epidemics through History

Jenice Jean Goveas
27 April 2020
Photo Source: welcomecollecton.org

Whether we have the grit and energy to deal with this pandemic which many compare to the fourth horseman of the apocalypse is for all to see in the coming days

"Ring a Ring o' Roses" one of the first nursery rhymes that each one of us naively sang as a child is believed to date back to the Great Plague of 1665. The rosy rash accompanied by Sneezing or coughing “A-tishoo! A-tishoo!” was a fatal symptom, therefore "all fall down" symbolised death. At a time when the entire world is talking about the New Covid-19 pandemic, it is apt to look back at some of the largest epidemics fought by humankind.  

Epidemic: From the Wrath of God to Vaccination to Social Distancing
Since times immemorial, humans have considered epidemics as the ‘Wrath of God’. The Bible mentions early Israelites receiving leprosy and plague as punishment for their sins. This unscientific perception often led to disastrous consequences.  Girolamo Fracastoro (1546) an Italian physician was among the first to explain the cause of disease by a concept of 'disease seeds'. The Father of Microbiology, Antoine Leewenhock (1674) was the first to see bacteria, yeast etc. under the microscope. 

John Snow (1854), the Father of Epidemiology used geography and statistical analysis to break the prevailing hypothesis that cholera was spread by miasmas and proved that it was indeed transmitted by tainted water or food consumption. Louis Pasteur in the late 1800s ascertained the significance of microbes and destroyed many myths regarding the spread of diseases. The Industrial Revolution and the later technological boom not only made the world a global village and brought people closer through trade but also simultaneously increased the risk of disease transmission, causing more epidemics blow into pandemics. 

In Homer’s “Odyssey” Zeus, says that humans always blame God for their suffering; “but they experience pain beyond their fate because of their own recklessness”. However, science and medicine also progressed exponentially enabling humans to battle various deadly diseases although we ourselves were responsible for many of them.

Epidemics: Down the History, from Plague to Corona
Going down mankind’s deadly memory lane of diseases, the first record is of the fourth century BC when Hippocrates described scarlet-fever-like symptoms. Another early epidemic was the Antonine Plague in AD 165 which is believed to have killed 6.5 million people. It was an outbreak of either smallpox or measles unknowingly carried by Roman soldiers. The bubonic Plague of Justinian that caused hand necrosis entered the Mediterranean region from China in 541 AD and killed 25 million people worldwide. The Black death or the plague of 1348-1350 is considered the most devastating pandemic in human history. The gangrene causing bacterium, Yersinia pestis wiped out 100 million people and is widely regarded as responsible for the European “Live for the moment” attitude. London's Great Plague killed 1,00,000 people in 1665-1666. Even though rats were the host of fleas which carried the disease, misinformation that pets were responsible for the plague along with misguided instructions to eradicate all cats and dogs in the cities skyrocketed the rat population, accelerating the plague.

However, accidents can prove to be blessings in disguise and the 1666 Great Fire that destroyed much of London assisted in putting an end to the epidemic.

It is interesting to note how Italy, today struggling to outwit the corona virus taught the world the practice of quarantine back in the 14th century while protecting coastal cities from plague epidemics. The term originates from the practice of anchoring ships for 40 days which translates to “quaranta giorni” in Italian. During1633-1634, Smallpox was brought by the European settlers to North America and it wiped out seventy per cent of the Native American population. It was only in 1770 that Edward Jenner developed a vaccine from cow pox and the last case of it was reported in 1949. In 1771, Bubonic plague struck Moscow. Quarantine measures imposed by officials infuriated and terrified the public resulting in widespread riots and destruction totalling a death of 2,00,000 people. 

Cholera pandemics have terrorised humanity since ages and the seventh pandemic is still ongoing causing 130,000 deaths a year. The third cholera pandemic of 1852 to 1859 that swept Asia, America, Africa and Russia was the deadliest cholera pandemic costing 10,00,000 lives. The 1918 Spanish flu was H1N1 and killed 75 million people most of whom were surprisingly young and healthy individuals. It later resurfaced in 1957 as the “Asian flu” and took away nearly 70,000 lives and again appeared in 2009 after which a vaccine was established. The deadly Ebola of 2014, affected the Central African counties of Congo and Sierra Leonne with over 11,000 deaths. Safe burial practices and strict quarantine helped contain the outbreaks. The rVSV-ZEBOV Ebola vaccine was employed for the first time to stop another outbreak in Congo in April 2018. The worst pandemic of this century is the ongoing Covid-19 which has affected more than one million people and killed about 65,000 individuals in 205 countries. Although an effective vaccine is yet to be discovered scientists have been pinning hopes on novel treatments like plasma therapy and nanoparticles to deal with the virus. 

The role of hygiene is highlighted in the Biblical story of an epidemic that struck the Philistines when they captured the Ark of the Covenant from the Israelites. The Philistines who took no sanitary precautions of the Levitical code became susceptible to the disease unlike Israelites who practiced disinfection techniques like burning the cart along with the dead oxen. In 1906, A cook nicknamed “Typhoid Mary” was a healthy carrier for typhoid virus and spread it to122 New Yorkers after which the epidemic escalated manifold until a vaccine was finally developed in 1911 and in 1948 antibiotic treatment was made available. In addition to vaccines, Modern sewage and water treatment facilities have helped control cholera but the virus is still present. 
Today, vaccines can greatly contain epidemics of diphtheria, measles and Polio. However, tuberculosis (TB) termed ‘White Plague’ is still a formidable killer. About 2 million people succumb to it each year, equivalent to seven Tsunamis annually. The increasing cases of multidrug and extreme drug resistant TB add to the scare. Influenza virus including coronavirus is another great threat as its strains easily mutate, making vaccinations ineffective.

After COVID-19
What is more horrifying is the belief that ancient epidemics like the black death are lying dormant in the third world animal population and could resurface anytime as massive outbreaks. A few prophesies like that of Nostredame also point to the same. The Biblical book of ‘Revelations’ mentioning “beasts of the earth” will have a part to play is considered as a reference to animal-borne diseases like the mad cow disease, the Bird Flu-H5N1, Nipah virus from pigs, and not to forget the New Covid-19 which broke out at an animal trade market in Wuhan. Predicting this outbreak did not require divine intervention. 

Even Bill Gates had in a TED talk in 2015 predicted that the biggest threat to mankind was not nuclear but microbial- something that we are not prepared for. This threat is real for now. For the first time in our lifetimes have we witnessed the entire world so helplessly holding hands like small children singing “Ring a Ring o' Roses”. Whether we have the grit and energy to deal with this pandemic which many compare to the fourth horseman of the apocalypse is for all to see in the coming days. 


PREVIOUS COMMENTS

The World This Quarter 
April 2026 | CWA # 2065

Lakshmi Venugopal Menon

The Middle East (Jan–Mar 2026):
The US-Iran War, Israel-Hamas Conflict and their interconnected fallouts
The World This Quarter 
April 2026 | CWA # 2064

Anwesha Ghosh

Afghanistan (Jan–Mar 2026):
Gender Repression, Leadership Rifts, Regional Realignments and Clashes with Pakistan
The World This Quarter 
April 2026 | CWA # 2063

Ramya B

Russia (Jan-Mar 2026)
Assertive Military Posture, Attempts for an Economic Turnaround and Search for Partners
The World This Quarter 
April 2026 | CWA # 2062

Himani Pant

Europe (Jan-Mar 2026)
Trade diversification & FTAs, Increased defence spending, Tightening irregular migration and Economic slowdown
The World This Quarter 
April 2026 | CWA # 2061

S Shaji

Africa (Jan-Mar 2026)
Elections, Civil Wars, Militancy and Peace Initiatives
The World This Quarter 
April 2026 | CWA # 2059

Adarsh Vijay

India and the World (Jan-Mar 2026)
Maintaining Strategic Autonomy, Balancing the US relations and Resetting the China ties 
The World This Quarter 
April 2026 | CWA # 2058

Nishchal N Pandey  & Mahesh Raj Bhatta

Nepal (Jan-Mar 2026)
Political Upheaval, Generational Change and Economic Uncertainty
The World This Quarter 
April 2026 | CWA # 2057

Bibhu Prasad Routray

Myanmar (Jan-Mar 2026)
An Illegitimate Regime’s Consolidation Game
The World This Quarter
April 2026 | CWA # 2056

Ashik J Bonofer

Southeast Asia (Jan-Mar 2026)
Deteriorating situation in Myanmar, Philippines as the ASEAN Chair, New government in Thailand, and Economic & Environmental challenges
The World This Quarter 
April 2026 | CWA # 2055

Haans J Freddy

East Asia (Jan-Mar 2026)
China’s military operations near Taiwan, Japan-China tensions and South Korea’s security challenges
The World This Quarter
April 2026 | CWA # 2052

Shreya Upadhyay

The United States (Jan-Mar 2026)
Tariffs, Ukraine, Iran and Operationalization of Trump’s World Order
March 2026 | CWA # 2039

Femy Francis

Trump-Xi Meeting
Why did Trump reschedule it? What does that mean?
March 2026 | CWA # 2035

Akshath Kaimal

Pakistan-Afghanistan Conflict
Broken ceasefire, Expanding military strikes and Worsening humanitarian situation
Global Politics Early Bird
March 2026 | CWA # 2033

Mahesh Bhatta

Nepal after elections:
Five major challenges for the new government
March 2026 | CWA # 2024

Lekshmi MK

The UN and the Iran-US War
UNSC Resolution 2817 between “Clear and Unified Message” and “Manifest Injustice”
March 2026 | CWA # 2023

Femy Francis

China’s Two Sessions 2026
New Five-Year Plan, Ethnic Unity Law, and an Enhanced Defence Budget
March 2026 | CWA # 2019

Akshath Kaimal

Rising Violence in Nigeria
Limited State Capacity, Multiple Actors, and a Complex Security Environment
March 2026 | CWA # 2012

Padmashree Anandhan

The War in Ukraine
Long-range strikes, Defence adaptation and the EU’s energy dependence
Global Politics Early Bird
March 2026 | CWA # 2010

Mahesh Bhatta

Nepal Elections 2026
The Rise of the “New” and the Fall of the “Old”
March 2026 | CWA # 2009

Sreemaya Nair

Nepal Elections 2026
Rise of a new leadership and Reset in political landscape
February 2026 | CWA # 1998

Anu Maria Joseph

Instability in Sudan
Response to the genocide call and the threats of a regional spillover
PR Commentary
February 2026 | CWA # 1985

Abhimanyu Solanki

Basant in Pakistan
The return of Basant, and what it signifies
February 2026 | CWA # 1977

Anu Maria Joseph

Violence in Nigeria
US military deployment amidst worsening insurgency
February 2026 | CWA # 1976

Lekshmi MK

The War in Ukraine
The Geneva Talks and Growing Negotiation Asymmetry
Pakistan in 2025
December 2025 | CWA # 1971

Vani Vyshnavi Jupudi

Pakistan Budget 2025-26
Legislating stabilisation under IMF discipline and coalition constraints
Pakistan in 2025
December 2025 | CWA # 1970

Aparna A Nair

Pakistan & China
Ten Years of China-Pakistan Economic Corridor (CPEC)
PR Explainer
November 2025 | CWA # 1968

Vani Vyshnavi Jupudi

Pakistan and the US
A New opening, or another cycle?
February 2026 | CWA # 1959

Yesasvi Koganti

UK and China
PM Keir Starmer’s visit and the Recalibration of Economic, Strategic, and Domestic ties
TWTW Note
January 2026 | CWA # 1946

R Preetha

The Davos Summit 2026
Five Major Takeaways from The World Economic Forum
State of Global Politics 2025
December 2025 | CWA # 1931

Padmashree Anandhan

NATO Summit 2025
State of Global Politics 2025
December 2025 | CWA # 1924

Padmashree Anandhan

NATO Summit 2025
This Week in History
August 2025 | CWA # 1801

R Preetha

28 August 1963
Martin Luther King's "I Have a Dream" speech and the Civil Rights Movement in the US
The World This Week
August 2025 | CWA # 1790

GP Team

The World This Week#323-324
The Trump-Putin meeting & the US-China tariff extension
TWTW note
August 2025 | CWA # 1780

Abhiruchi Chowdhury

Trump tariffs:
Weaponization of access to the US economy
The World This Week
August 2025 | CWA # 1779

GP Team

The World This Week#322
US tariffs on India, Brazil and Canada & the EU-US trade deal
This Week in History
August 2025 | CWA # 1778

Lekshmi MK

28 July 1914
Austria-Hungary declares war on Serbia, starting the First World War
Global Politics Explainer
July 2025 | CWA # 1770

Abhiruchi Chowdhury

Pakistan-Afghanistan relations:
Why the focus on terrorism, refugees, and Uzbekistan as the third partner?
The World This Week
July 2025 | CWA # 1769

GP Team

The World This Week#321
Indian PM Modi's visit to the Maldives I Elections to the Upper House in Japan
Global Politics Explainer
July 2025 | CWA # 1762

Lekshmi MK

Ocean Darkening: 
What is the phenomenon? What are its effects? And who are more vulnerable?
Global Politics Explainer
July 2025 | CWA # 1749

R Preetha

Africa as the Hunger Epicenter
Of the 13 Global Hunger Hotspots, 8 are in Africa: Five reasons why
The World This Week
July 2025 | CWA # 1748

GP Team

The World This Week #318
PM Modi’s Visit to Trinidad and Tobago & Ghana, One big beautiful bill, and Quad Foreign Ministers Meeting
Global Politics Explainer
July 2025 | CWA # 1744

Chittrothu Vaihali

EU-Canada Summit 2025
What is security and defence partnership all about?
Conflict Weekly
July 2025 | CWA # 1742

IPRI Team

Conflict Weekly # 287-88
The 12 Day War and the Congo-Rwanda Peace Deal
Global Politics Explainer
July 2025 | CWA # 1738

Fleur Elizabeth Philip

Thailand and Cambodia
What was the phone call between PM Shinawatra and President of Senate Hun Sen? What is the border dispute between the two? Why has this become an issue?
TWTW Note
June 2025 | CWA # 1735

Padmashree Anandhan

NATO Summit 2025:
Trump making Europe great again
The World This Week
June 2025 | CWA # 1734

GP Team

The World This Week #317
NATO Summit 2025 and Russia-Mali bilateral agreements
Global Politics Explainer
June 2025 | CWA # 1733

Ananya Dinesh

China and the Pacific Islands 
What was the recent China-PIC joint statement about? What it says, and what it means?
TWTW Note
June 2025 | CWA # 1728

M Kejia

G7 Summit 2025:
The Focus on the Middle East and Trade negotiations
TWTW Note
June 2025 | CWA # 1727

Aparna A Nair

Second China-Central Asia Summit:
China’s continuing search for regional partners, and the emphasis on the BRI
The World This Week
June 2025 | CWA # 1726

GP Team

The World This Week #316
China-Central Asia Summit in Kazakhstan, and the G7 Summit in Canada
Global Politics Explainer
June 2025 | CWA # 1725

Brighty Ann Sarah, R Preetha, Santhiya M, Aparna A Nair & M Kejia

Operation Midnight Hammer: US bombs three nuclear sites in Iran
What were the three Iranian nuclear sites that were targeted? What are the B2 Bombers and Bunker Buster Bombs? What do these attacks mean? What Next?
Conflict Weekly
June 2025 | CWA # 1724

IPRI Team

Conflict Weekly #286
The Spiralling Israel-Iran Crisis, and the Dangerous Hunger Hotspots
Global Politics Explainer
June 2025 | CWA # 1721

Rizwana Banu S and Santhiya M

Who are the Afrikaners?
Why is Trump interested in the Afrikaner question in South Africa?
Global Politics Explainer
June 2025 | CWA # 1720

Lekshmi MK

New WMO Report on Arctic Warming
What are the social, economic and environmental implications of Arctic warming
Global Politics Explainer
June 2025 | CWA # 1719

J Yamini  

China’s EV Surge
What contributes to the rise of BYD
Global Politics Explainer
June 2025 | CWA # 1717

J Yamini

Gender Violence in Pakistan:
What are the larger issues in the Noor Mukadam case?
TWTW Note
June 2025 | CWA # 1715

Femy Francis

The US-China:
On Tariffs, Rare Earths and Visas
The World This Week
June 2025 | CWA # 1713

GP Team

The World This Week #315
The UN Ocean Conference in France and the US-China Meeting in London
Conflict Weekly
June 2025 | CWA # 1709

IPRI Team

Conflict Weekly #284-285
Cambodia-Thailand Border Tensions, Protests in the US, and the Indigenous Māori question in New Zealand
The World This Week
June 2025 | CWA # 1705

GP Team

The World This Week #314
Elections in South Korea and Poland I China and the Pacific Island Countries I Bangladesh Election Announcement 2026
Global Politics Explainer
June 2025 | CWA # 1703

M Kejia 

Sagarmatha Sambaad in Nepal
Kathmandu’s Global Agenda for the Himalayas
Global Politics Explainer
June 2025 | CWA # 1700

R Preetha

Ethiopia bans the TPLF
What does the TPLF ban mean for the Pretoria agreement? What next for Ethiopia?
TWTW Note
June 2025 | CWA # 1694

Aashish Ganeshan

The US:
Harvard vs Trump Administration
The World This Week
June 2025 | CWA # 1691

GP Team

The World This Week #313
China-ASEAN-GCC Summit I President Macron's visit to South East Asia I Trump Vs Harvard
The World This Week
May 2025 | CWA # 1690

GP Team

The World This Week #312
Elections in Romania, Portugal & Poland I UK-EU Summit
CW Note
May 2025 | CWA # 1689

Padmashree Anandhan

Ukraine
Continuing Russia’s Aerial Attacks, despite exchange of prisoners
CW Note
May 2025 | CWA # 1688

Ayan Datta

Gaza
The Humanitarian Crisis and Israel’s Renewed Offensive
TWTW Note
May 2025 | CWA # 1685

Aparna A Nair

UK-EU Summit:
First step towards a reset
TWTW Note
May 2025 | CWA # 1683

Aashish Ganeshan

Elections in Portugal:
The Rise of Chega Party and the Search for Political Stability
TWTW Note
May 2025 | CWA # 1679

Aashish Ganeshan

US in the Middle Easr
Trump’s visit to Saudi Arabia, Qatar and UAE
TWTW Note
May 2025 | CWA # 1678

Gauri Gupta

China in Latin America
China-CELAC forum: Strengthening ties with Latin America and Caribbean
The World This Week
May 2025 | CWA # 1677

GP Team

The World This Week #310-311
China in Latin America and the Carribbean I Trump's Middle East Visit I Denmark as the new Arctic Chair
CW Note
May 2025 | CWA # 1675

Lekshmi MK

Turkey:
PKK disbands after 40 years of armed insurgency
CW Note
May 2025 | CWA # 1673

Padmashree Anandhan

Ukraine:
The Discussion in Turkiye and the Elusive Ceasefire
CW Note
May 2025 | CWA # 1672

D Suba Chandran

India and Pakistan:
De-escalation and the “New Normal”
CW Note
May 2025 | CWA # 1671

Abhiruchi Chowdhury

US, Ukraine and Russia:
Air attacks amidst a Minerals deal and Ceasefire Proposals
Global Politics Early Bird
May 2025 | CWA # 1670

Fleur Elizabeth Philip

Singapore Elections in 2025:
People’s Action Party (PAP) Wins, Again
TWTW Note
May 2025 | CWA # 1667

R Preetha and Brighty Ann Sarah

East Asia:
Tough Tariff Negotiations with the US
TWTW Note
May 2025 | CWA # 1666

Padmashree Anandhan

The US-Ukraine
The mineral deal with the US
Conflict Weekly
May 2025 | CWA # 1665
Conflict Weekly # 280-81
India-Pakistan De-escalation I Ukraine Discussion in Istanbul I The Battle over Port Sudan I Disbanding of PKK in Turkiye I France-Algeria Diplomatic Tensions
Global Politics Early Bird
May 2025 | CWA # 1663

R Preetha

Canada Elections 2025:
What do the results convey? What next for Mark Carney?
NIAS Global Politics Database
March 2024 | CWA # 1251

NIAS Africa Team

Africa This Week
NIAS Global Politics Database
February 2024 | CWA # 1226

NIAS Africa Team

Africa This Week
The War in Ukraine
October 2023 | CWA # 1091

Annem Naga Bindhu Madhuri

Issues for Europe
IPRI Quarterly Forecasts I Triggers, Trends, and Trajectories
July 2023 | CWA # 1012

Bibhu Prasad Routray

Myanmar continues to burn
2022: The World This Year
December 2022 | CWA # 879

Padmashree Anandhan

The Ukraine War
Europe: Heatwaves, Wildfires, Droughts, and Ice Melt in Alps
November 2022 | CWA # 838

Rishma Banerjee

Tracing Europe's droughts
NIAS Africa Weekly
March 2022 | CWA # 705

NIAS Africa Team

In Focus: Libya
The World This Week: 150th Issue
December 2021 | CWA # 630

GP Team

Europe in 2021
Pakistan Reader
October 2021 | CWA # 588

Abigail Miriam Fernandez

TLP is back again
NIAS Fortnightly on Science, Technology & International Relations
August 2021 | CWA # 528

STIR Team

Space Tourism
Science, Technology and International Relations
September 2019 | CWA # 162

Lakshman Chakravarthy N

5G: A Primer
South Asia Monthly Brief (Nov 2018)
December 2018 | CWA # 71

Mahesh Bhatta

Nepal
South Asia Monthly Brief (Nov 2018)
December 2018 | CWA # 70

Nasima Khatoon

The Maldives
South Asia Monthly Brief (Nov 2018)
December 2018 | CWA # 69

Harini Madhusudan

India
South Asia Monthly Brief (Nov 2018)
December 2018 | CWA # 68

Sourina Bej

Bangladesh
South Asia Monthly Brief (Nov 2018)
December 2018 | CWA # 67

Seetha Lakshmi Dinesh Iyer

Afghanistan